Al Hain-Cole, who has a solid previous record against Guardiola's side, is picking Wolves to keep things close at the Etihad.
Manchester City will be looking to bounce back from their defeat when they host Wolves at the Etihad Stadium on Saturday.
In midweek, City was defeated 2-1 by RB Leipzig in the Champions League, ending a run of seven consecutive triumphs.
Manchester City vs Wolves latest odds
Man City, on the other hand, is overwhelming 1/7 (1.14) favorites with bet365 to return to winning ways against a team they have only beaten three times in their last seven meetings.
Bruno Lage's team has only won one of their past five games, and Wolves are 18/1 (19.0) outsiders to win at the champions' home ground, or 7/1 (8.0) to record a creditable draw.
Manchester City vs Wolves first goalscorer
Gabriel Jesus is the 9/2 (5.50) favorite to break the deadlock against a defense he scored three goals against in the two previous meetings, while Bernardo Silva is a tempting 15/2 (8.50) bet after scoring five goals in his last five league games.
After scoring his team's single goal in the last five matches, Raul Jimenez is the 14/1 (15.0) first goalscorer favorite, with striking partner Hee-Chan Hwang at 20/1. (21.0).
Manchester City vs Wolves preview
The visitors know how to frustrate the Etihad Stadium crowd, as they are one of only five clubs to keep Pep Guardiola's squad from scoring in a home league game since his appointment in 2016.
Indeed, they have maintained a clean sheet in two of their previous four visits to this ground, and in last weekend's 1-0 defeat, they came within a whisker of becoming the first team to prevent Liverpool from scoring this season.
Wolves, who have only conceded three goals and scored only once in their previous five games, are likely to set themselves up in a similar defensive manner.
Manchester City vs Wolves tips & predictions
Nonetheless, given City's recent form and an assortment of attacking potential, even money (2.0) on them getting all three points in a game with under 3.5 goals seems generous.
At the time of writing, all odds were correct. Please use caution when gambling.
